Compound Detail
CHEMBL73341
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Basic Information
| ChEMBL ID | CHEMBL73341 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BFELQLHLUNQIHL-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
437.6
MW (Da)
4.38
ALogP
5
HBA
0
HBD
62.6
PSA (Ų)
0.63
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M2 CHEMBL211 | Ki | 8.1 | 8.1 | 8.0 | 1 |
| Muscarinic acetylcholine receptor M1 CHEMBL216 | Ki | 6.93 | 6.93 | 117.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Ki | = | 8.0 | nM | 8.1 | Binding affinity towards the cloned human Muscarinic acetylcholine receptor M2 | 11055332 |
| Muscarinic acetylcholine receptor M1 | Ki | = | 117.0 | nM | 6.93 | Binding affinity towards the cloned human Muscarinic acetylcholine receptor M1 | 11055332 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11055332 | 10.1016/s0960-894x(00)00438-8 | Muscarinic acetylcholine receptor M1 | 1 |
| 11055332 | 10.1016/s0960-894x(00)00438-8 | Muscarinic acetylcholine receptor M2 | 1 |
| 11055332 | 10.1016/s0960-894x(00)00438-8 | Muscarinic acetylcholine receptors; M1 & M2 | 1 |
Data from ChEMBL 36 via Core Engine