Compound Detail
CHEMBL73397
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL73397 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VLMWJPBYPKMRMA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
360.5
MW (Da)
4.67
ALogP
4
HBA
1
HBD
71.4
PSA (Ų)
0.54
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Oryctolagus cuniculus CHEMBL374 | IC50 | 6.12 | 6.12 | 760.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Oryctolagus cuniculus | IC50 | = | 760.0 | nM | 6.12 | In vitro concentration that reduced U-44069-induced contraction of the rabbit ao... | 2769691 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2769691 | 10.1021/jm00129a030 | Oryctolagus cuniculus | 4 |
Data from ChEMBL 36 via Core Engine