Compound Detail
CHEMBL77492
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL77492 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MRDDDUTZQYNACV-VIFPVBQESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
373.2
MW (Da)
2.08
ALogP
5
HBA
3
HBD
82.0
PSA (Ų)
0.69
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL339 | IC50 | 8.72 | 8.72 | 1.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | IC50 | = | 1.9 | nM | 8.72 | The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]... | 1973734 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1973734 | 10.1021/jm00170a040 | D(2) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine