Compound Detail
CHEMBL77926
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Basic Information
| ChEMBL ID | CHEMBL77926 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VASOZZCCIPIYAT-ONEGZZNKSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
409.3
MW (Da)
4.88
ALogP
6
HBA
1
HBD
68.9
PSA (Ų)
0.48
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily A member 3 CHEMBL4633 | Kd | 6.1 | 6.1 | 800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily A member 3 | Kd | = | 800.0 | nM | 6.1 | Dissociation constant for the blockage of voltage-gated potassium channel subuni... | 15084131 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15084131 | 10.1021/jm030523s | Potassium voltage-gated channel subfamily A member 3 | 1 |
Data from ChEMBL 36 via Core Engine