Compound Detail
CHEMBL79271
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL79271 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KERCIXYHQBGDCI-RITPCOANSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
137.2
MW (Da)
0.48
ALogP
2
HBA
2
HBD
40.7
PSA (Ų)
0.59
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL5076 | Ki | 8.15 | 8.15 | 7.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 7.0 | nM | 8.15 | Inhibition of [3H]N-alpha-methylhistamine binding to guinea pig brain Histamine ... | 9871662 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9871662 | 10.1016/s0960-894x(98)00020-1 | Histamine H3 receptor | 1 |
| 9871662 | 10.1016/s0960-894x(98)00020-1 | Histamine H1 receptor | 1 |
Data from ChEMBL 36 via Core Engine