Compound Detail
CHEMBL86517
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Basic Information
| ChEMBL ID | CHEMBL86517 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SYZHMHDRCWEOQG-WGSAOQKQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
360.5
MW (Da)
4.41
ALogP
3
HBA
1
HBD
35.2
PSA (Ų)
0.75
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.34
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL339 | Ki | 6.34 | 6.34 | 457.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | Ki | = | 457.0 | nM | 6.34 | In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by ... | 9003524 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9003524 | 10.1021/jm960597m | Rattus norvegicus | 2 |
| 9003524 | 10.1021/jm960597m | D(2) dopamine receptor | 1 |
| 9003524 | 10.1021/jm960597m | Mus musculus | 1 |
Data from ChEMBL 36 via Core Engine