Compound Detail
CHEMBL87504
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Basic Information
| ChEMBL ID | CHEMBL87504 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WYVYDCVFEZZZCK-MXVIHJGJSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
374.5
MW (Da)
4.66
ALogP
3
HBA
1
HBD
35.2
PSA (Ų)
0.72
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(2) dopamine receptor CHEMBL339 | Ki | 7.07 | 7.07 | 85.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(2) dopamine receptor | Ki | = | 85.0 | nM | 7.07 | In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by ... | 9003524 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9003524 | 10.1021/jm960597m | Rattus norvegicus | 2 |
| 9003524 | 10.1021/jm960597m | D(2) dopamine receptor | 1 |
| 9003524 | 10.1021/jm960597m | Mus musculus | 1 |
Data from ChEMBL 36 via Core Engine