Compound Detail
CHEMBL899
LANSOPRAZOLE SULFIDE Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL899 |
| Name | LANSOPRAZOLE SULFIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CCHLMSUZHFPSFC-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
353.4
MW (Da)
4.50
ALogP
4
HBA
1
HBD
50.8
PSA (Ų)
0.69
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.34
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mycobacterium tuberculosis CHEMBL360 | IC50 | 6.34 | 6.285 | 460.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mycobacterium tuberculosis | IC50 | = | 460.0 | nM | 6.34 | Antibacterial activity against wild type Mycobacterium tuberculosis H37Rv assess... | 29549838 |
| Mycobacterium tuberculosis | IC50 | = | 590.0 | nM | 6.23 | Antibacterial activity against Mycobacterium tuberculosis infected in mouse RAW2... | 29549838 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29549838 | 10.1016/j.ejmech.2018.03.020 | Mycobacterium tuberculosis | 3 |
| 36804747 | 10.1016/j.bmc.2023.117212 | Mycobacterium tuberculosis | 2 |
| 9599229 | 10.1021/jm970165r | Helicobacter pylori | 1 |
| 9599229 | 10.1021/jm970165r | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine