Compound Detail
CHEMBL92507
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL92507 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DSXNASZPNPWGEB-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
256.3
MW (Da)
3.71
ALogP
4
HBA
0
HBD
36.9
PSA (Ų)
0.62
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 7.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.8 | 7.8 | 16.0 | 1 |
| Plasmodium falciparum CHEMBL364 | IC50 | 7.29 | 7.205 | 51.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 16.0 | nM | 7.8 | Evaluated for the neurotoxicity against NB2a Neuroblastoma cells. | 10893313 |
| Plasmodium falciparum | IC50 | = | 51.0 | nM | 7.29 | Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 | 10893313 |
| Plasmodium falciparum | IC50 | = | 76.0 | nM | 7.12 | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 | 10893313 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10893313 | 10.1021/jm0000766 | Plasmodium falciparum | 2 |
| 10893313 | 10.1021/jm0000766 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine