Compound Detail
CHEMBL92890
HYDROXYPREGNENOLONE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL92890 |
| Name | HYDROXYPREGNENOLONE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LKQDFQLSEHWIRK-UKBVDAKRSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
334.5
MW (Da)
3.71
ALogP
3
HBA
2
HBD
57.5
PSA (Ų)
0.77
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticosteroid-binding globulin CHEMBL2421 | Ki | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticosteroid-binding globulin | Ki | = | 10000.0 | nM | 5.0 | Binding affinity to human CBG receptor (corticosteroid-binding globulins) | 15139751 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9651159 | 10.1021/jm970732a | Corticosteroid-binding globulin | 1 |
| 3599019 | 10.1021/jm00390a002 | ADMET | 1 |
| 15139751 | 10.1021/jm030364c | Corticosteroid-binding globulin | 1 |
| 10966742 | 10.1021/jm000941m | Corticosteroid-binding globulin | 1 |
| 12672239 | 10.1021/jm021077w | Corticosteroid-binding globulin | 1 |
| 10836148 | 10.1146/annurev.pharmtox.40.1.581 | UDP-glucuronosyltransferase 2B4 | 1 |
| 10836148 | 10.1146/annurev.pharmtox.40.1.581 | UDP-glucuronosyltransferase 2B7 | 1 |
Data from ChEMBL 36 via Core Engine