Compound Detail
CHEMBL95444
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Basic Information
| ChEMBL ID | CHEMBL95444 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YGLAVYDBJCLVRF-MBNMGENJSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
277.3
MW (Da)
1.37
ALogP
3
HBA
3
HBD
100.6
PSA (Ų)
0.73
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 5.29 | 5.29 | 5070.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 5070.0 | nM | 5.29 | Antagonistic activity was evaluated by using ACPD sensitive [3H]-glutamate bindi... | 9873635 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9873635 | 10.1016/s0960-894x(98)00510-1 | Rattus norvegicus | 1 |
| 9873635 | 10.1016/s0960-894x(98)00510-1 | Metabotropic glutamate receptor 2 | 1 |
| 9873635 | 10.1016/s0960-894x(98)00510-1 | Metabotropic glutamate receptor 3 | 1 |
Data from ChEMBL 36 via Core Engine