Compound Detail
CHEMBL95521
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL95521 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZOLVPLVVVCAWCK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
420.4
MW (Da)
3.93
ALogP
6
HBA
1
HBD
72.9
PSA (Ų)
0.65
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 CHEMBL260 | IC50 | 7.38 | 7.38 | 42.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 | IC50 | = | 42.0 | nM | 7.38 | Inhibition against Mitogen-activated protein kinase p38 alpha | 11597418 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11597418 | 10.1016/s0960-894x(01)00570-4 | Mitogen-activated protein kinase 14 | 1 |
| 11597418 | 10.1016/s0960-894x(01)00570-4 | Mus musculus | 1 |
| - | 10.6019/CHEMBL3988181 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine