Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9HCR9. Use UniProt Q9HCR9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9HCR9 as the stable identity anchor, then attach disease evidence before program review.
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Review this target as Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, mapped to UniProt Q9HCR9. Sequence length is 933 aa.
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This review treats Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A as ChEMBL target CHEMBL2717, mapped to UniProt Q9HCR9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9HCR9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A |
| UniProt Accession | Q9HCR9 |
| Component Type | Protein |
| Sequence Length | 933 aa |
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Review this target as Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, mapped to UniProt Q9HCR9. Sequence length is 933 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5437525 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL282515 | 8.85 | IC50 | 1.4 | Preclinical |
| CHEMBL284070 | 8.7 | IC50 | 2.01 | Preclinical |
| CHEMBL33518 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL4217054 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL418594 | 8.46 | IC50 | 3.5 | Preclinical |
| CHEMBL4292389 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL33121 | 8.38 | IC50 | 4.2 | Preclinical |
| CHEMBL285737 | 8.37 | IC50 | 4.3 | Preclinical |
| CHEMBL286309 | 8.33 | IC50 | 4.7 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 90 | 131 | 5.9 |
| cell-based format | 26 | 61 | 7.1 |
| assay format | 4 | 1 | 7.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 0 | — |
| cell-based format | 2 | 3 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 6.5 |