Presequence protease, mitochondrial · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q5JRX3. Use UniProt Q5JRX3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q5JRX3 as the stable identity anchor, then attach disease evidence before program review.
Presequence protease, mitochondrial
Review this target as Presequence protease, mitochondrial, mapped to UniProt Q5JRX3. Sequence length is 1037 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Presequence protease, mitochondrial as ChEMBL target CHEMBL3124731, mapped to UniProt Q5JRX3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Presequence protease, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q5JRX3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Presequence protease, mitochondrial |
| UniProt Accession | Q5JRX3 |
| Component Type | Protein |
| Sequence Length | 1037 aa |
Presequence protease, mitochondrial
Review this target as Presequence protease, mitochondrial, mapped to UniProt Q5JRX3. Sequence length is 1037 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3127264 | 7.92 | EC50 | 12.0 | Preclinical |
| CHEMBL6020304 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL6004569 | 7.64 | IC50 | 23.0 | Preclinical |
| CHEMBL5981431 | 7.47 | IC50 | 34.0 | Preclinical |
| CHEMBL6059875 | 7.38 | IC50 | 42.0 | Preclinical |
| CHEMBL5957037 | 7.31 | IC50 | 49.0 | Preclinical |
| CHEMBL3127263 | 7.24 | EC50 | 57.0 | Preclinical |
| CHEMBL5925037 | 7.24 | IC50 | 58.0 | Preclinical |
| CHEMBL5968328 | 7.17 | IC50 | 68.0 | Preclinical |
| CHEMBL5809136 | 6.7 | IC50 | 200.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 10 | 16 | 6.5 |
| assay format | 5 | 0 | — |