Heat sensitive channel TRPV3 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt Q4QYD9. Use UniProt Q4QYD9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q4QYD9 as the stable identity anchor, then attach disease evidence before program review.
Transient receptor potential cation channel subfamily V member 3
Review this target as Heat sensitive channel TRPV3, mapped to UniProt Q4QYD9. ChEMBL maps the protein component as Transient receptor potential cation channel subfamily V member 3. Sequence length is 791 aa.
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This review treats Heat sensitive channel TRPV3 as ChEMBL target CHEMBL3879847, mapped to UniProt Q4QYD9. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Heat sensitive channel TRPV3 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q4QYD9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transient receptor potential cation channel subfamily V member 3 |
| UniProt Accession | Q4QYD9 |
| Component Type | Protein |
| Sequence Length | 791 aa |
Transient receptor potential cation channel subfamily V member 3
Review this target as Heat sensitive channel TRPV3, mapped to UniProt Q4QYD9. ChEMBL maps the protein component as Transient receptor potential cation channel subfamily V member 3. Sequence length is 791 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3943485 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL3943485 | 6.77 | EC50 | 170.0 | Preclinical |
| CHEMBL190461 | 6.29 | EC50 | 510.0 | Approved |
| CHEMBL190461 | 6.12 | IC50 | 750.0 | Approved |
| CHEMBL3890789 | 5.92 | EC50 | 1200.0 | Preclinical |
| CHEMBL3979367 | 5.85 | EC50 | 1400.0 | Preclinical |
| CHEMBL497044 | 5.68 | EC50 | 2100.0 | Preclinical |
| CHEMBL497044 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL3979367 | 5.66 | IC50 | 2200.0 | Preclinical |
| CHEMBL3983336 | 5.62 | EC50 | 2400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 19 | 5.2 |