Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P19793. Use UniProt P19793 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P19793 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor RXR-alpha
Review this target as Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha, mapped to UniProt P19793. ChEMBL maps the protein component as Retinoic acid receptor RXR-alpha. Sequence length is 462 aa.
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This review treats Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha as ChEMBL target CHEMBL3885613, mapped to UniProt P19793. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P19793 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor RXR-alpha |
| UniProt Accession | P19793 |
| Component Type | Protein |
| Sequence Length | 462 aa |
Retinoic acid receptor RXR-alpha
Review this target as Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha, mapped to UniProt P19793. ChEMBL maps the protein component as Retinoic acid receptor RXR-alpha. Sequence length is 462 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5266566 | 9.1 | EC50 | 0.7943 | Preclinical |
| CHEMBL1023 | 8.3 | EC50 | 5.012 | Approved |
| CHEMBL3780763 | 7.9 | EC50 | 12.59 | Preclinical |
| CHEMBL3781132 | 7.9 | EC50 | 12.59 | Preclinical |
| CHEMBL3780806 | 6.3 | EC50 | 501.19 | Preclinical |
| CHEMBL509 | 6.05 | EC50 | 900.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 5 | 7.4 |
| protein complex format | 1 | 1 | 9.1 |