Type-1 angiotensin II receptor · SINGLE PROTEIN · Oryctolagus cuniculus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P34976. Use UniProt P34976 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P34976 as the stable identity anchor, then attach disease evidence before program review.
Type-1 angiotensin II receptor
Review this target as Type-1 angiotensin II receptor, mapped to UniProt P34976. Sequence length is 359 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Type-1 angiotensin II receptor as ChEMBL target CHEMBL3948, mapped to UniProt P34976. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Type-1 angiotensin II receptor is the right protein anchor across sources, using UniProt P34976 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Type-1 angiotensin II receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | P34976 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Type-1 angiotensin II receptor |
| UniProt Accession | P34976 |
| Component Type | Protein |
| Sequence Length | 359 aa |
Type-1 angiotensin II receptor
Review this target as Type-1 angiotensin II receptor, mapped to UniProt P34976. Sequence length is 359 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL138690 | 10.37 | IC50 | 0.043 | Preclinical |
| CHEMBL293511 | 10.3 | Kd | 0.05012 | Preclinical |
| CHEMBL416477 | 10.3 | Kd | 0.05012 | Preclinical |
| CHEMBL418226 | 10.3 | Kd | 0.05012 | Preclinical |
| CHEMBL265797 | 10.28 | IC50 | 0.052 | Preclinical |
| CHEMBL48242 | 10.26 | IC50 | 0.055 | Preclinical |
| CHEMBL152106 | 10.2 | Kd | 0.0631 | Preclinical |
| CHEMBL339672 | 10.14 | IC50 | 0.072 | Preclinical |
| CHEMBL341828 | 10.14 | IC50 | 0.072 | Preclinical |
| CHEMBL343309 | 10.1 | IC50 | 0.08 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 30 | 432 | 8.1 |
| single protein format | 28 | 303 | 8.4 |
| cell membrane format | 12 | 195 | 8.9 |
| assay format | 2 | 28 | 7.7 |
| organism-based format | 1 | 23 | 9.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 29 | 168 | 8.1 |
| assay format | 11 | 37 | 7.7 |
| cell membrane format | 3 | 91 | 7.8 |