Alpha-1B adrenergic receptor · SINGLE PROTEIN · Cricetulus griseus
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As of 2026-09-14Protein identity stays anchored to UniProt G3HDX1. Use UniProt G3HDX1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt G3HDX1 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 2B
Review this target as Alpha-1B adrenergic receptor, mapped to UniProt G3HDX1. ChEMBL maps the protein component as 5-hydroxytryptamine receptor 2B. Sequence length is 291 aa.
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This review treats Alpha-1B adrenergic receptor as ChEMBL target CHEMBL3988626, mapped to UniProt G3HDX1. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alpha-1B adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cricetulus griseus |
| UniProt | G3HDX1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 2B |
| UniProt Accession | G3HDX1 |
| Component Type | Protein |
| Sequence Length | 291 aa |
5-hydroxytryptamine receptor 2B
Review this target as Alpha-1B adrenergic receptor, mapped to UniProt G3HDX1. ChEMBL maps the protein component as 5-hydroxytryptamine receptor 2B. Sequence length is 291 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1215 | 8.0 | EC50 | 10.0 | Approved |
| CHEMBL134 | 7.08 | EC50 | 83.0 | Approved |
| CHEMBL1079 | 6.49 | EC50 | 322.0 | Approved |
| CHEMBL778 | 6.44 | EC50 | 364.0 | Approved |
| CHEMBL844 | 6.03 | EC50 | 943.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 5 | 6.8 |