Casein kinase 2 · PROTEIN COMPLEX · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P67874. Use UniProt P67874 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P67874 as the stable identity anchor, then attach disease evidence before program review.
Casein kinase II subunit beta
Review this target as Casein kinase 2, mapped to UniProt P67874. ChEMBL maps the protein component as Casein kinase II subunit beta. Sequence length is 215 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Casein kinase 2 as ChEMBL target CHEMBL3988629, mapped to UniProt P67874. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Casein kinase 2 is the right protein anchor across sources, using UniProt P67874 as the stable mapping.
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| Preferred Name | Casein kinase 2 |
| Target Type | PROTEIN COMPLEX |
| Organism | Rattus norvegicus |
| UniProt | P67874 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Casein kinase II subunit beta |
| UniProt Accession | P67874 |
| Component Type | Protein |
| Sequence Length | 215 aa |
Casein kinase II subunit beta
Review this target as Casein kinase 2, mapped to UniProt P67874. ChEMBL maps the protein component as Casein kinase II subunit beta. Sequence length is 215 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL373937 | 7.4 | Ki | 40.0 | Preclinical |
| CHEMBL6246 | 7.4 | IC50 | 40.0 | Clinical |
| CHEMBL273101 | 7.22 | Ki | 60.0 | Preclinical |
| CHEMBL270724 | 7.11 | Ki | 77.0 | Preclinical |
| CHEMBL273101 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL3974619 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL270724 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL29898 | 6.96 | IC50 | 110.0 | Preclinical |
| CHEMBL373937 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL376505 | 6.85 | IC50 | 140.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 22 | 6.3 |