Use UniProt Q61851 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL4066 Target Snapshot
Fibroblast growth factor receptor 3 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q61851. Use UniProt Q61851 as the stable identity anchor, then attach disease evidence before program review.
Fibroblast growth factor receptor 3
Review this target as Fibroblast growth factor receptor 3, mapped to UniProt Q61851. Sequence length is 801 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Fibroblast growth factor receptor 3 as ChEMBL target CHEMBL4066, mapped to UniProt Q61851. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Fibroblast growth factor receptor 3 is the right protein anchor across sources, using UniProt Q61851 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Fibroblast growth factor receptor 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q61851 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Fibroblast growth factor receptor 3 |
| UniProt Accession | Q61851 |
| Component Type | Protein |
| Sequence Length | 801 aa |
Fibroblast growth factor receptor 3
How to read this target
Review this target as Fibroblast growth factor receptor 3, mapped to UniProt Q61851. Sequence length is 801 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5187371 | 8.27 | IC50 | 5.4 | Preclinical |
| CHEMBL5180631 | 8.26 | IC50 | 5.5 | Preclinical |
| CHEMBL5203027 | 8.14 | IC50 | 7.2 | Preclinical |
| CHEMBL5206837 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL5184953 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL5202408 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5200643 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL5286909 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL5172121 | 7.66 | IC50 | 22.0 | Preclinical |
| CHEMBL5199231 | 7.54 | IC50 | 29.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 3 assays, 20 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 20 | 7.2 |