Angiotensin-converting enzyme · SINGLE PROTEIN · Oryctolagus cuniculus
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As of 2026-09-13Protein identity stays anchored to UniProt P12822. Use UniProt P12822 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P12822 as the stable identity anchor, then attach disease evidence before program review.
Angiotensin-converting enzyme
Review this target as Angiotensin-converting enzyme, mapped to UniProt P12822. Sequence length is 1310 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Angiotensin-converting enzyme as ChEMBL target CHEMBL4074, mapped to UniProt P12822. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Angiotensin-converting enzyme |
| Target Type | SINGLE PROTEIN |
| Organism | Oryctolagus cuniculus |
| UniProt | P12822 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Angiotensin-converting enzyme |
| UniProt Accession | P12822 |
| Component Type | Protein |
| Sequence Length | 1310 aa |
Angiotensin-converting enzyme
Review this target as Angiotensin-converting enzyme, mapped to UniProt P12822. Sequence length is 1310 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL112589 | 10.68 | IC50 | 0.021 | Preclinical |
| CHEMBL113612 | 10.68 | IC50 | 0.021 | Preclinical |
| CHEMBL324898 | 10.6 | IC50 | 0.025 | Preclinical |
| CHEMBL323879 | 10.55 | IC50 | 0.028 | Preclinical |
| CHEMBL112922 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL554951 | 10.05 | IC50 | 0.09 | Preclinical |
| CHEMBL114018 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL324676 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL324703 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL115153 | 10.0 | IC50 | 0.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 109 | 533 | 7.1 |
| tissue-based format | 13 | 120 | 7.1 |
| organism-based format | 9 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 5 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 3 | 4.5 |