TEL/AXL · CHIMERIC PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P30530. Use UniProt P30530 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P30530 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein kinase receptor UFO
Review this target as TEL/AXL, mapped to UniProt P30530. ChEMBL maps the protein component as Tyrosine-protein kinase receptor UFO. Sequence length is 894 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats TEL/AXL as ChEMBL target CHEMBL4523666, mapped to UniProt P30530. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | TEL/AXL |
| Target Type | CHIMERIC PROTEIN |
| Organism | Homo sapiens |
| UniProt | P30530 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein kinase receptor UFO |
| UniProt Accession | P30530 |
| Component Type | Protein |
| Sequence Length | 894 aa |
Tyrosine-protein kinase receptor UFO
Review this target as TEL/AXL, mapped to UniProt P30530. ChEMBL maps the protein component as Tyrosine-protein kinase receptor UFO. Sequence length is 894 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4581972 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL4576727 | 8.37 | IC50 | 4.3 | Preclinical |
| CHEMBL3301622 | 8.07 | IC50 | 8.5 | Approved |
| CHEMBL4516515 | 8.02 | IC50 | 9.6 | Preclinical |
| CHEMBL4529955 | 6.99 | IC50 | 102.5 | Preclinical |
| CHEMBL4519811 | 6.67 | IC50 | 213.9 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 6 | 7.8 |