Casein kinase I isoform gamma-3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9Y6M4. Use UniProt Q9Y6M4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Y6M4 as the stable identity anchor, then attach disease evidence before program review.
Casein kinase I isoform gamma-3
Review this target as Casein kinase I isoform gamma-3, mapped to UniProt Q9Y6M4. Sequence length is 447 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Casein kinase I isoform gamma-3 as ChEMBL target CHEMBL5084, mapped to UniProt Q9Y6M4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Casein kinase I isoform gamma-3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9Y6M4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Casein kinase I isoform gamma-3 |
| UniProt Accession | Q9Y6M4 |
| Component Type | Protein |
| Sequence Length | 447 aa |
Casein kinase I isoform gamma-3
Review this target as Casein kinase I isoform gamma-3, mapped to UniProt Q9Y6M4. Sequence length is 447 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1999931 | 8.1 | Ki | 7.943 | Preclinical |
| CHEMBL1965660 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL1969588 | 7.7 | Ki | 19.95 | Preclinical |
| CHEMBL2003638 | 7.7 | Ki | 19.95 | Preclinical |
| CHEMBL1990288 | 7.5 | Ki | 31.62 | Preclinical |
| CHEMBL1981079 | 7.5 | Ki | 31.62 | Preclinical |
| CHEMBL2006439 | 7.5 | Ki | 31.62 | Preclinical |
| CHEMBL5434183 | 7.43 | Kd | 37.0 | Preclinical |
| CHEMBL1996066 | 7.4 | Ki | 39.81 | Preclinical |
| CHEMBL1966628 | 7.3 | Ki | 50.12 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 169 | 24 | 6.1 |
| assay format | 29 | 3 | 6.2 |
| cell-based format | 10 | 0 | — |
| subcellular format | 5 | 8 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 154 | 6.0 |