Assay Detail
ADMET
CHEMBL1001844
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Inhibition of CYP2C9
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Tetrahydro anthranilic acid as a surrogate for anthranilic acid: application to the discovery of potent niacin receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.29 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL482480 | — | — | 1 | 5.92 |
| CHEMBL482481 | — | — | 1 | 5.29 |
| CHEMBL236163 | — | — | 1 | 4.66 |
| CHEMBL483934 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL482480 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL482481 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL236163 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL483934 | — | IC50 | > | 100000.0 | nM | - |