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Assay Detail

CHEMBL1047436

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitrypanosomal activity against Trypanosoma cruzi trypomastigotes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma cruzi
Confidence 1 — Organism
Curated By Autocuration

Target

Trypanosoma cruzi (CHEMBL368)
Type ORGANISM
Organism Trypanosoma cruzi

Publication

Neglected tropical diseases: multi-target-directed ligands in the search for novel lead candidates against Trypanosoma and Leishmania.
Cavalli A, Bolognesi ML.
J Med Chem (2009) 52 : 7339 -7359
PubMed 19606868 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.76 4.76

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL454129 1 4.76
CHEMBL110 BENZNIDAZOLE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL454129 IC50 = 17300.0 nM 4.76
CHEMBL110 BENZNIDAZOLE IC50 = 103600.0 nM -