Assay Detail
Binding
CHEMBL1072346
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Binding affinity to FGF1 by surface plasmon-based solution affinity assay
17
Total Activities
17
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 17 | 6.54 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL604568 | — | — | 1 | 7.00 |
| CHEMBL602113 | — | — | 1 | 6.93 |
| CHEMBL590011 | — | — | 1 | 6.92 |
| CHEMBL603122 | — | — | 1 | 6.80 |
| CHEMBL604368 | — | — | 1 | 6.80 |
| CHEMBL604366 | — | — | 1 | 6.79 |
| CHEMBL604570 | — | — | 1 | 6.72 |
| CHEMBL602307 | — | — | 1 | 6.72 |
| CHEMBL590012 | — | — | 1 | 6.70 |
| CHEMBL590010 | — | — | 1 | 6.68 |
| CHEMBL589773 | — | — | 1 | 6.62 |
| CHEMBL4297162 | MUPARFOSTAT SODIUM | -1.0 | 1 | 6.62 |
| CHEMBL602114 | — | — | 1 | 6.55 |
| CHEMBL604569 | — | — | 1 | 6.44 |
| CHEMBL2029015 | — | — | 1 | 6.10 |
| CHEMBL590013 | — | — | 1 | 5.64 |
| CHEMBL604367 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL604568 | — | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL602113 | — | Kd | = | 118.0 | nM | 6.93 |
| CHEMBL590011 | — | Kd | = | 120.0 | nM | 6.92 |
| CHEMBL603122 | — | Kd | = | 160.0 | nM | 6.80 |
| CHEMBL604368 | — | Kd | = | 160.0 | nM | 6.80 |
| CHEMBL604366 | — | Kd | = | 161.0 | nM | 6.79 |
| CHEMBL604570 | — | Kd | = | 190.0 | nM | 6.72 |
| CHEMBL602307 | — | Kd | = | 190.0 | nM | 6.72 |
| CHEMBL590012 | — | Kd | = | 200.0 | nM | 6.70 |
| CHEMBL590010 | — | Kd | = | 210.0 | nM | 6.68 |
| CHEMBL589773 | — | Kd | = | 240.0 | nM | 6.62 |
| CHEMBL4297162 | MUPARFOSTAT SODIUM | Kd | = | 240.0 | nM | 6.62 |
| CHEMBL602114 | — | Kd | = | 280.0 | nM | 6.55 |
| CHEMBL604569 | — | Kd | = | 360.0 | nM | 6.44 |
| CHEMBL2029015 | — | Kd | = | 790.0 | nM | 6.10 |
| CHEMBL590013 | — | Kd | = | 2300.0 | nM | 5.64 |
| CHEMBL604367 | — | Kd | = | 6000.0 | nM | 5.22 |