Assay Detail
Binding
CHEMBL1099474
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human FAAH-mediated hydrolysis of [3H]AEA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.58 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1079421 | PHENMEDIPHAM | — | 1 | 6.82 |
| CHEMBL1079935 | AMPEROZIDE | 2.0 | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1079421 | PHENMEDIPHAM | IC50 | = | 152.0 | nM | 6.82 |
| CHEMBL1079935 | AMPEROZIDE | IC50 | = | 455.0 | nM | 6.34 |