Assay Detail
ADMET
CHEMBL1107369
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Cytotoxicity against human BJ cells assessed as viable cells after 72 hrs by calcein AM assay
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | BJ |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic activities of several geranyl-substituted flavanones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 16 | 5.24 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463675 | — | — | 1 | 5.33 |
| CHEMBL1094304 | OLOMOUCINE II | — | 1 | 5.27 |
| CHEMBL223256 | NYMPHAEOL A | — | 1 | 5.23 |
| CHEMBL1094618 | — | — | 1 | 5.12 |
| CHEMBL253152 | — | — | 1 | - |
| CHEMBL36016 | DIAZIQUONE | 2.0 | 1 | - |
| CHEMBL66 | (+)-TAXIFOLIN | — | 1 | - |
| CHEMBL1096940 | — | — | 1 | - |
| CHEMBL1096939 | KUWANON E | — | 1 | - |
| CHEMBL517927 | TOMENTODIPLACONE B | — | 1 | - |
| CHEMBL459252 | TOMENTODIPLACONE | — | 1 | - |
| CHEMBL374130 | BONANNIONE A | — | 1 | - |
| CHEMBL463842 | — | — | 1 | - |
| CHEMBL459258 | — | — | 1 | - |
| CHEMBL399121 | HESPERETIN | 0.5 | 1 | - |
| CHEMBL9352 | NARINGENIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463675 | — | EC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL1094304 | OLOMOUCINE II | EC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL223256 | NYMPHAEOL A | EC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL1094618 | — | EC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL253152 | — | EC50 | < | 10000.0 | nM | - |
| CHEMBL36016 | DIAZIQUONE | EC50 | < | 10000.0 | nM | - |
| CHEMBL66 | (+)-TAXIFOLIN | EC50 | > | 10000.0 | nM | - |
| CHEMBL1096940 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL1096939 | KUWANON E | EC50 | > | 10000.0 | nM | - |
| CHEMBL517927 | TOMENTODIPLACONE B | EC50 | > | 10000.0 | nM | - |
| CHEMBL459252 | TOMENTODIPLACONE | EC50 | > | 10000.0 | nM | - |
| CHEMBL374130 | BONANNIONE A | EC50 | > | 10000.0 | nM | - |
| CHEMBL463842 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL459258 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL399121 | HESPERETIN | EC50 | > | 10000.0 | nM | - |
| CHEMBL9352 | NARINGENIN | EC50 | > | 10000.0 | nM | - |