Assay Detail
Binding
CHEMBL1614549
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3). (Class of assay: confirmatory) [Related pubchem assays: 746 ]
362
Total Activities
362
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Category | confirmatory |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 362 | 4.66 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1339933 | — | — | 1 | 6.40 |
| CHEMBL1445111 | — | — | 1 | 6.30 |
| CHEMBL1568840 | — | — | 1 | 6.09 |
| CHEMBL1360489 | — | — | 1 | 6.03 |
| CHEMBL1420552 | — | — | 1 | 5.82 |
| CHEMBL1545599 | — | — | 1 | 5.77 |
| CHEMBL1343539 | — | — | 1 | 5.74 |
| CHEMBL1352869 | — | — | 1 | 5.74 |
| CHEMBL1307032 | — | — | 1 | 5.72 |
| CHEMBL1579483 | — | — | 1 | 5.69 |
| CHEMBL1423096 | — | — | 1 | 5.67 |
| CHEMBL315708 | — | — | 1 | 5.63 |
| CHEMBL1562951 | — | — | 1 | 5.58 |
| CHEMBL1543571 | — | — | 1 | 5.50 |
| CHEMBL1526703 | — | — | 1 | 5.49 |
| CHEMBL1372085 | — | — | 1 | 5.47 |
| CHEMBL1525187 | — | — | 1 | 5.40 |
| CHEMBL1502894 | — | — | 1 | 5.39 |
| CHEMBL1429270 | — | — | 1 | 5.38 |
| CHEMBL1367073 | — | — | 1 | 5.38 |
| CHEMBL1416028 | — | — | 1 | 5.37 |
| CHEMBL1463060 | — | — | 1 | 5.34 |
| CHEMBL1345273 | — | — | 1 | 5.34 |
| CHEMBL1344527 | — | — | 1 | 5.31 |
| CHEMBL1613269 | — | — | 1 | 5.30 |
| CHEMBL1606045 | — | — | 1 | 5.26 |
| CHEMBL1329293 | — | — | 1 | 5.25 |
| CHEMBL1598218 | — | — | 1 | 5.23 |
| CHEMBL1537195 | — | — | 1 | 5.22 |
| CHEMBL1486096 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1339933 | — | IC50 | = | 401.0 | nM | 6.40 |
| CHEMBL1445111 | — | IC50 | = | 502.0 | nM | 6.30 |
| CHEMBL1568840 | — | IC50 | = | 809.0 | nM | 6.09 |
| CHEMBL1360489 | — | IC50 | = | 929.0 | nM | 6.03 |
| CHEMBL1420552 | — | IC50 | = | 1505.0 | nM | 5.82 |
| CHEMBL1545599 | — | IC50 | = | 1701.0 | nM | 5.77 |
| CHEMBL1352869 | — | IC50 | = | 1819.0 | nM | 5.74 |
| CHEMBL1343539 | — | IC50 | = | 1819.0 | nM | 5.74 |
| CHEMBL1307032 | — | IC50 | = | 1892.0 | nM | 5.72 |
| CHEMBL1579483 | — | IC50 | = | 2023.0 | nM | 5.69 |
| CHEMBL1423096 | — | IC50 | = | 2164.0 | nM | 5.67 |
| CHEMBL315708 | — | IC50 | = | 2341.0 | nM | 5.63 |
| CHEMBL1562951 | — | IC50 | = | 2619.0 | nM | 5.58 |
| CHEMBL1543571 | — | IC50 | = | 3136.0 | nM | 5.50 |
| CHEMBL1526703 | — | IC50 | = | 3259.0 | nM | 5.49 |
| CHEMBL1372085 | — | IC50 | = | 3356.0 | nM | 5.47 |
| CHEMBL1525187 | — | IC50 | = | 3962.0 | nM | 5.40 |
| CHEMBL1502894 | — | IC50 | = | 4058.0 | nM | 5.39 |
| CHEMBL1429270 | — | IC50 | = | 4217.0 | nM | 5.38 |
| CHEMBL1367073 | — | IC50 | = | 4189.0 | nM | 5.38 |
| CHEMBL1416028 | — | IC50 | = | 4261.0 | nM | 5.37 |
| CHEMBL1463060 | — | IC50 | = | 4604.0 | nM | 5.34 |
| CHEMBL1345273 | — | IC50 | = | 4535.0 | nM | 5.34 |
| CHEMBL1344527 | — | IC50 | = | 4873.0 | nM | 5.31 |
| CHEMBL1613269 | — | IC50 | = | 5004.0 | nM | 5.30 |
| CHEMBL1606045 | — | IC50 | = | 5460.0 | nM | 5.26 |
| CHEMBL1329293 | — | IC50 | = | 5586.0 | nM | 5.25 |
| CHEMBL1598218 | — | IC50 | = | 5942.0 | nM | 5.23 |
| CHEMBL1537195 | — | IC50 | = | 5959.0 | nM | 5.22 |
| CHEMBL1486096 | — | IC50 | = | 6203.0 | nM | 5.21 |
| CHEMBL1386265 | — | IC50 | = | 6331.0 | nM | 5.20 |
| CHEMBL1391385 | — | IC50 | = | 6263.0 | nM | 5.20 |
| CHEMBL1559474 | — | IC50 | = | 6628.0 | nM | 5.18 |
| CHEMBL1579427 | — | IC50 | = | 6827.0 | nM | 5.17 |
| CHEMBL1518163 | — | IC50 | = | 6771.0 | nM | 5.17 |
| CHEMBL1465291 | — | IC50 | = | 6677.0 | nM | 5.17 |
| CHEMBL1301287 | — | IC50 | = | 6691.0 | nM | 5.17 |
| CHEMBL1447733 | — | IC50 | = | 6935.0 | nM | 5.16 |
| CHEMBL1520998 | — | IC50 | = | 6931.0 | nM | 5.16 |
| CHEMBL1462869 | — | IC50 | = | 7159.0 | nM | 5.14 |
| CHEMBL1349350 | — | IC50 | = | 7190.0 | nM | 5.14 |
| CHEMBL1527065 | — | IC50 | = | 7366.0 | nM | 5.13 |
| CHEMBL1324221 | — | IC50 | = | 7930.0 | nM | 5.10 |
| CHEMBL1500025 | — | IC50 | = | 7984.0 | nM | 5.10 |
| CHEMBL1381330 | — | IC50 | = | 7928.0 | nM | 5.10 |
| CHEMBL1498885 | — | IC50 | = | 7873.0 | nM | 5.10 |
| CHEMBL1477311 | — | IC50 | = | 7969.0 | nM | 5.10 |
| CHEMBL1303401 | — | IC50 | = | 8418.0 | nM | 5.08 |
| CHEMBL1392784 | — | IC50 | = | 8417.0 | nM | 5.08 |
| CHEMBL2005690 | — | IC50 | = | 8813.0 | nM | 5.05 |