Compound Detail
CHEMBL1344527
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Basic Information
| ChEMBL ID | CHEMBL1344527 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JLYPYACZXPBHLU-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
233.3
MW (Da)
2.80
ALogP
3
HBA
1
HBD
50.2
PSA (Ų)
0.83
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.81
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Major prion protein CHEMBL4869 | IC50 | 5.81 | 5.81 | 1558.0 | 1 |
| Mitogen-activated protein kinase 10 CHEMBL2637 | IC50 | 5.31 | 5.31 | 4873.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Major prion protein | IC50 | = | 1558.0 | nM | 5.81 | PubChem BioAssay. TRFRET-based cell-based high throughput dose response assay to... | - |
| Mitogen-activated protein kinase 10 | IC50 | = | 4873.0 | nM | 5.31 | PUBCHEM_BIOASSAY: Dose response biochemical screening assay for inhibitors of c-... | - |
Data from ChEMBL 36 via Core Engine