Assay Detail
Binding
CHEMBL1645735
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Inhibition of human carbonic anhydrase 9 by Lineweaver-Burk curves
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Characterization and anions inhibition studies of an α-carbonic anhydrase from the teleost fish Dicentrarchus labrax.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89295 | SODIUM AZIDE | — | 1 | 5.30 |
| CHEMBL1141 | POTASSIUM IODIDE | 4.0 | 1 | - |
| CHEMBL1644028 | THIOCYANATE SODIUM | -1.0 | 1 | - |
| CHEMBL1644029 | POTASSIUM NITRATE | 4.0 | 1 | - |
| CHEMBL1644030 | POTASSIUM BROMIDE | -1.0 | 1 | - |
| CHEMBL1200731 | POTASSIUM CHLORIDE | 4.0 | 1 | - |
| CHEMBL1644027 | POTASSIUM FLUORIDE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89295 | SODIUM AZIDE | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL1141 | POTASSIUM IODIDE | Ki | = | 7000000.0 | nM | - |
| CHEMBL1644028 | THIOCYANATE SODIUM | Ki | = | 130000.0 | nM | - |
| CHEMBL1644029 | POTASSIUM NITRATE | Ki | = | 46000000.0 | nM | - |
| CHEMBL1644030 | POTASSIUM BROMIDE | Ki | = | 16000000.0 | nM | - |
| CHEMBL1200731 | POTASSIUM CHLORIDE | Ki | = | 33000000.0 | nM | - |
| CHEMBL1644027 | POTASSIUM FLUORIDE | Ki | = | 48000000.0 | nM | - |