Assay Detail
Functional
CHEMBL2019289
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen 2 infected in african green monkey Vero cells expressing red fluorescent protein after 3 days by fluorescence analysis
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phosphonium lipocations as antiparasitic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.44 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2017468 | — | — | 1 | 5.80 |
| CHEMBL2017479 | — | — | 1 | 5.80 |
| CHEMBL110 | BENZNIDAZOLE | 4.0 | 1 | 5.68 |
| CHEMBL2017480 | — | — | 1 | 5.62 |
| CHEMBL2017483 | — | — | 1 | 5.57 |
| CHEMBL2017470 | — | — | 1 | 5.52 |
| CHEMBL2017476 | — | — | 1 | 5.43 |
| CHEMBL2017477 | — | — | 1 | 5.40 |
| CHEMBL2017482 | — | — | 1 | 5.27 |
| CHEMBL2017485 | — | — | 1 | 5.03 |
| CHEMBL2017484 | — | — | 1 | 4.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2017468 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL2017479 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL110 | BENZNIDAZOLE | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL2017480 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL2017483 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL2017470 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL2017476 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL2017477 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL2017482 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL2017485 | — | IC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL2017484 | — | IC50 | = | 17300.0 | nM | 4.76 |