Assay Detail
Functional
CHEMBL2090635
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Cytotoxicity against human A2780 cells after 96 hrs by SRB assay
15
Total Activities
15
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Tormentic acid derivatives: synthesis and apoptotic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 15 | 5.05 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2089029 | — | — | 1 | 6.10 |
| CHEMBL2089030 | — | — | 1 | 5.58 |
| CHEMBL2089031 | — | — | 1 | 5.39 |
| CHEMBL2089027 | — | — | 1 | 5.36 |
| CHEMBL2089022 | — | — | 1 | 5.31 |
| CHEMBL2089028 | — | — | 1 | 5.05 |
| CHEMBL2089025 | EUSCAPHIC ACID METHYL ESTER | — | 1 | 4.89 |
| CHEMBL2086420 | — | — | 1 | 4.75 |
| CHEMBL2089026 | — | — | 1 | 4.75 |
| CHEMBL2089024 | — | — | 1 | 4.72 |
| CHEMBL600614 | TORMENTIC ACID METHYL ESTER | — | 1 | 4.62 |
| CHEMBL439053 | — | — | 1 | 4.61 |
| CHEMBL239296 | — | — | 1 | 4.55 |
| CHEMBL239077 | TOMENTIC ACID | — | 1 | - |
| CHEMBL2089023 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2089029 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL2089030 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL2089031 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL2089027 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL2089022 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL2089028 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL2089025 | EUSCAPHIC ACID METHYL ESTER | IC50 | = | 12800.0 | nM | 4.89 |
| CHEMBL2086420 | — | IC50 | = | 17800.0 | nM | 4.75 |
| CHEMBL2089026 | — | IC50 | = | 17600.0 | nM | 4.75 |
| CHEMBL2089024 | — | IC50 | = | 18900.0 | nM | 4.72 |
| CHEMBL600614 | TORMENTIC ACID METHYL ESTER | IC50 | = | 23900.0 | nM | 4.62 |
| CHEMBL439053 | — | IC50 | = | 24300.0 | nM | 4.61 |
| CHEMBL239296 | — | IC50 | = | 28100.0 | nM | 4.55 |
| CHEMBL239077 | TOMENTIC ACID | IC50 | > | 30000.0 | nM | - |
| CHEMBL2089023 | — | IC50 | > | 30000.0 | nM | - |