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Compound Detail

CHEMBL239296

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CC(=O)O[C@H]1[C@H](O)C[C@]2(C)[C@H]3CC=C4[C@H]5[C@](C(=O)O)(CC[C@@H](C)[C@@]5(C)O)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C

Basic Information

ChEMBL ID CHEMBL239296
Phase Preclinical
Structure Type MOL
InChI Key HWGMGZJITMCAFQ-BGJCYSRJSA-N
4
Targets
4
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

530.8
MW (Da)
5.75
ALogP
5
HBA
3
HBD
104.1
PSA (Ų)
0.31
QED
2
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C32H50O6
MW 530.75
Aromatic Rings 0
Heavy Atoms 38
NP-Likeness 3.36

Activity Summary

IC50 4 meas. best 4.58

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
MCF7
CHEMBL387
IC50 4.58 4.58 26200.0 1
A2780
CHEMBL614004
IC50 4.55 4.55 28100.0 1
K562
CHEMBL385
IC50 4.25 4.25 56610.0 1
NON-PROTEIN TARGET
CHEMBL3879801
IC50 4.14 4.14 72870.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine