Assay Detail
ADMET
CHEMBL2157016
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Cytotoxicity against Chinese hamster Xrs-6 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | XRS6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL449905 | MAKALUVAMINE A | — | 1 | 7.10 |
| CHEMBL2153157 | MAKALUVAMINE B | — | 1 | 7.10 |
| CHEMBL540397 | MAKALUVAMINE C | — | 1 | 7.10 |
| CHEMBL453817 | MAKALUVAMINE D | — | 1 | 7.10 |
| CHEMBL509186 | MAKALUVAMINE E | — | 1 | 7.10 |
| CHEMBL509890 | MAKALUVAMINE F | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL449905 | MAKALUVAMINE A | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL2153157 | MAKALUVAMINE B | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL540397 | MAKALUVAMINE C | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL453817 | MAKALUVAMINE D | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL509186 | MAKALUVAMINE E | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL509890 | MAKALUVAMINE F | IC50 | = | 80.0 | nM | 7.10 |