Assay Detail
Functional
CHEMBL3214840
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PubChem BioAssay. SAR analysis of small molecule antagonists of Gli-SUFU in a luminescent reporter assay - Set 1. (Class of assay: confirmatory)
60
Total Activities
58
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 60 | 7.01 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1393367 | — | — | 2 | 7.62 |
| CHEMBL3187872 | — | — | 1 | 7.43 |
| CHEMBL1438842 | — | — | 1 | 7.42 |
| CHEMBL3184876 | — | — | 1 | 7.13 |
| CHEMBL3185423 | — | — | 1 | 6.75 |
| CHEMBL3185613 | — | — | 1 | 6.25 |
| CHEMBL1523428 | — | — | 1 | 6.20 |
| CHEMBL3185857 | — | — | 1 | - |
| CHEMBL3187752 | — | — | 1 | - |
| CHEMBL3186429 | — | — | 1 | - |
| CHEMBL3186476 | — | — | 1 | - |
| CHEMBL3186610 | — | — | 1 | - |
| CHEMBL3186785 | — | — | 1 | - |
| CHEMBL3187107 | — | — | 1 | - |
| CHEMBL3187121 | — | — | 1 | - |
| CHEMBL3187241 | — | — | 1 | - |
| CHEMBL3187493 | — | — | 1 | - |
| CHEMBL3187538 | — | — | 1 | - |
| CHEMBL3185694 | — | — | 1 | - |
| CHEMBL3182966 | — | — | 1 | - |
| CHEMBL1583316 | — | — | 1 | - |
| CHEMBL3184611 | — | — | 1 | - |
| CHEMBL3184558 | — | — | 1 | - |
| CHEMBL3184277 | — | — | 1 | - |
| CHEMBL3183966 | — | — | 1 | - |
| CHEMBL3183804 | — | — | 1 | - |
| CHEMBL3183725 | — | — | 1 | - |
| CHEMBL3183586 | — | — | 1 | - |
| CHEMBL3183417 | — | — | 1 | - |
| CHEMBL3182548 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1393367 | — | IC50 | = | 24.2 | nM | 7.62 |
| CHEMBL3187872 | — | IC50 | = | 37.0 | nM | 7.43 |
| CHEMBL1438842 | — | IC50 | = | 37.8 | nM | 7.42 |
| CHEMBL1393367 | — | IC50 | = | 56.6 | nM | 7.25 |
| CHEMBL3184876 | — | IC50 | = | 74.1 | nM | 7.13 |
| CHEMBL3185423 | — | IC50 | = | 176.0 | nM | 6.75 |
| CHEMBL3185613 | — | IC50 | = | 556.0 | nM | 6.25 |
| CHEMBL1523428 | — | IC50 | = | 636.0 | nM | 6.20 |
| CHEMBL3183682 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187241 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3183227 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3182557 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3182383 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3182177 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3188640 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187517 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187538 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187493 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3188146 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3183962 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3184327 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3185202 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3185558 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3185831 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3186180 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3186748 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3182966 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187528 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187975 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3183417 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3183725 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3183804 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3183966 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3184277 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3182703 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3184558 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3182201 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3184611 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3183586 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL1583316 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187121 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187752 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3185694 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187814 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3185857 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3186429 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3186476 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3186610 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3186785 | — | IC50 | > | 11700.0 | nM | - |
| CHEMBL3187107 | — | IC50 | > | 11700.0 | nM | - |