Compound Detail
CHEMBL3184876
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Basic Information
| ChEMBL ID | CHEMBL3184876 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WBTDHYCVVQRPLG-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
296.4
MW (Da)
3.11
ALogP
4
HBA
1
HBD
58.1
PSA (Ų)
0.95
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.46
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Zinc finger protein GLI1 CHEMBL5007 | IC50 | 7.46 | 7.295 | 35.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Zinc finger protein GLI1 | IC50 | = | 35.0 | nM | 7.46 | PubChem BioAssay. SAR analysis of small molecule antagonists of Gli-SUFU in a lu... | - |
| Zinc finger protein GLI1 | IC50 | = | 74.1 | nM | 7.13 | PubChem BioAssay. SAR analysis of small molecule antagonists of Gli-SUFU in a lu... | - |
Data from ChEMBL 36 via Core Engine