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Assay Detail

CHEMBL3364350

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Human respiratory syncytial virus A2 ATCC VR-1540 infected in Vero 76 cells after 5 days by plaque reduction assays
19
Total Activities
19
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human respiratory syncytial virus A2
Cell Type Vero 76
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines.
Loddo R, Briguglio I, Corona P, Piras S, Loriga M, Paglietti G, Carta A, Sanna G, Giliberti G, Ibba C, Farci P, La Colla P.
Eur J Med Chem (2014) 84 : 8 -16
PubMed 25014745 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 19 5.07 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL564201 6-AZAURIDINE 1 5.92
CHEMBL3317509 1 4.92
CHEMBL3317510 1 4.85
CHEMBL3317508 1 4.58
CHEMBL237143 1 -
CHEMBL3317499 1 -
CHEMBL3317500 1 -
CHEMBL3317501 1 -
CHEMBL3317474 1 -
CHEMBL3317475 1 -
CHEMBL3317502 1 -
CHEMBL3317503 1 -
CHEMBL1940452 1 -
CHEMBL3317505 1 -
CHEMBL3317506 1 -
CHEMBL3317507 1 -
CHEMBL3317511 1 -
CHEMBL3317512 1 -
CHEMBL3317504 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL564201 6-AZAURIDINE EC50 = 1200.0 nM 5.92
CHEMBL3317509 EC50 = 12000.0 nM 4.92
CHEMBL3317510 EC50 = 14000.0 nM 4.85
CHEMBL3317508 EC50 = 26000.0 nM 4.58
CHEMBL237143 EC50 > 100000.0 nM -
CHEMBL3317499 EC50 > 73000.0 nM -
CHEMBL3317500 EC50 > 100000.0 nM -
CHEMBL3317501 EC50 > 100000.0 nM -
CHEMBL3317474 EC50 > 100000.0 nM -
CHEMBL3317475 EC50 > 50000.0 nM -
CHEMBL3317502 EC50 > 100000.0 nM -
CHEMBL3317503 EC50 > 40000.0 nM -
CHEMBL1940452 EC50 > 100000.0 nM -
CHEMBL3317505 EC50 > 100000.0 nM -
CHEMBL3317506 EC50 > 100000.0 nM -
CHEMBL3317507 EC50 > 100000.0 nM -
CHEMBL3317511 EC50 > 90000.0 nM -
CHEMBL3317512 EC50 > 100000.0 nM -
CHEMBL3317504 EC50 > 100000.0 nM -