Assay Detail
ADMET
CHEMBL3532833
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP2D6 (unknown origin) assessed as sparteine oxidation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.10 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL814 | FLUVOXAMINE | 4.0 | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL814 | FLUVOXAMINE | Ki | = | 8000.0 | nM | 5.10 |