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Assay Detail

CHEMBL3802425

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiparasitic activity against Trypanosoma brucei infected in mouse L929 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma brucei
Cell Type L929
Confidence 1 — Organism
Curated By Autocuration

Target

Trypanosoma brucei (CHEMBL612849)
Type ORGANISM
Organism Trypanosoma brucei

Publication

Repurposing strategies for tropical disease drug discovery.
Klug DM, Gelb MH, Pollastri MP.
Bioorg Med Chem Lett (2016) 26 : 2569 -2576
PubMed 27080183 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.29 6.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1688757 1 6.43
CHEMBL1688741 1 6.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1688757 EC50 = 370.0 nM 6.43
CHEMBL1688741 EC50 = 720.0 nM 6.14