Assay Detail
Functional
CHEMBL4142807
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Anti-Trichomonas activity against Trichomonas vaginalis JT assessed as reduction in parasite growth after 24 hrs by haemocytometry
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trichomonas vaginalis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Recent developments in anti-Trichomonas research: An update review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.55 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1502 | PANTOPRAZOLE | 4.0 | 1 | 7.12 |
| CHEMBL1219 | RABEPRAZOLE | 4.0 | 1 | 6.98 |
| CHEMBL1503 | OMEPRAZOLE | 4.0 | 1 | 6.92 |
| CHEMBL480 | LANSOPRAZOLE | 4.0 | 1 | 6.91 |
| CHEMBL125 | MILTEFOSINE | 4.0 | 1 | 4.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1502 | PANTOPRAZOLE | IC50 | = | 75.6 | nM | 7.12 |
| CHEMBL1219 | RABEPRAZOLE | IC50 | = | 105.7 | nM | 6.98 |
| CHEMBL1503 | OMEPRAZOLE | IC50 | = | 121.6 | nM | 6.92 |
| CHEMBL480 | LANSOPRAZOLE | IC50 | = | 121.8 | nM | 6.91 |
| CHEMBL125 | MILTEFOSINE | IC50 | = | 14500.0 | nM | 4.84 |