Assay Detail
Functional
CHEMBL4178811
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Chikungunya virus LR2006 OPY1 infected in BHK cells measured at 14 hrs post infection by luciferase reporter gene assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
The medicinal chemistry of Chikungunya virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.80 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1200959 | METHDILAZINE | 4.0 | 1 | 4.95 |
| CHEMBL479 | THIORIDAZINE | 4.0 | 1 | 4.83 |
| CHEMBL1378 | THIETHYLPERAZINE | 4.0 | 1 | 4.82 |
| CHEMBL1206 | ETHOPROPAZINE | 4.0 | 1 | 4.80 |
| CHEMBL71 | CHLORPROMAZINE | 4.0 | 1 | 4.80 |
| CHEMBL567 | PERPHENAZINE | 4.0 | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1200959 | METHDILAZINE | IC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL479 | THIORIDAZINE | IC50 | = | 14900.0 | nM | 4.83 |
| CHEMBL1378 | THIETHYLPERAZINE | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1206 | ETHOPROPAZINE | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL71 | CHLORPROMAZINE | IC50 | = | 15700.0 | nM | 4.80 |
| CHEMBL567 | PERPHENAZINE | IC50 | = | 25100.0 | nM | 4.60 |