Assay Detail
Functional
CHEMBL4234776
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen strain C2C4 amastigote forms harboring LacZ infected in rat L6 cells after 96 hrs by CPRG/Nonidet reagent based photometric method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Cell Type | L6 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.93 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4245127 | — | — | 1 | 5.15 |
| CHEMBL4251480 | — | — | 1 | 4.70 |
| CHEMBL110 | BENZNIDAZOLE | 4.0 | 1 | - |
| CHEMBL4249696 | — | — | 1 | - |
| CHEMBL4242138 | — | — | 1 | - |
| CHEMBL4244656 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4245127 | — | IC50 | = | 7140.0 | nM | 5.15 |
| CHEMBL4251480 | — | IC50 | = | 20140.0 | nM | 4.70 |
| CHEMBL110 | BENZNIDAZOLE | IC50 | = | 0.5 | ug.mL-1 | - |
| CHEMBL4249696 | — | IC50 | - | — | - | |
| CHEMBL4242138 | — | IC50 | - | — | - | |
| CHEMBL4244656 | — | IC50 | - | — | - |