Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4338056

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs by spectrophotometry based broth microdilution assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterococcus faecalis
Confidence 1 — Organism
Curated By Autocuration

Target

Enterococcus faecalis (CHEMBL362)
Type ORGANISM
Organism Enterococcus faecalis

Publication

Trivirensols: Selectively Bacteriostatic Sesquiterpene Trimers from the Australian Termite Nest-Derived Fungus Trichoderma virens CMB-TN16.
Jiao WH, Salim AA, Khalil ZG, Dewapriya P, Lin HW, Butler MS, Capon RJ.
J Nat Prod (2019) 82 : 3165 -3175
PubMed 31625738 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.48 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4436622 1 6.00
CHEMBL4463460 1 5.80
CHEMBL4524936 1 5.10
CHEMBL4454696 1 5.00
CHEMBL4521700 1 -
CHEMBL4457702 1 -
CHEMBL4476583 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4436622 IC50 = 1000.0 nM 6.00
CHEMBL4463460 IC50 = 1600.0 nM 5.80
CHEMBL4524936 IC50 = 8000.0 nM 5.10
CHEMBL4454696 IC50 = 10000.0 nM 5.00
CHEMBL4521700 IC50 - -
CHEMBL4457702 IC50 - -
CHEMBL4476583 IC50 - -