Assay Detail
Functional
CHEMBL4415731
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma cruzi Y amastigotes infected in Swiss mouse primary cardiac cells replenished for every 48 hrs for 168 hrs by geimsa staining based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Pyrrolo[2,3-<i>b</i>]pyridine (1,7-Dideazapurine) Nucleoside Analogues as Anti-<i>Trypanosoma cruzi</i> Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.76 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4446605 | — | — | 1 | 7.05 |
| CHEMBL110 | BENZNIDAZOLE | 4.0 | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4446605 | — | EC50 | = | 89.0 | nM | 7.05 |
| CHEMBL110 | BENZNIDAZOLE | EC50 | = | 350.0 | nM | 6.46 |