Assay Detail
Functional
CHEMBL5369003
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against wildtype Trypanosoma brucei S427 bloodstream form
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and Biophysical and Biological Studies of <i>N</i>-Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.81 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1631694 | FEXINIDAZOLE | 4.0 | 1 | 6.00 |
| CHEMBL290960 | NIFURTIMOX | 4.0 | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1631694 | FEXINIDAZOLE | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL290960 | NIFURTIMOX | EC50 | = | 2400.0 | nM | 5.62 |