Assay Detail
Functional
CHEMBL655390
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro cytotoxicity against CEM cells
22
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis and antiviral activity of oxaselenolane nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 22 | 4.00 | 4.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433859 | — | — | 3 | 4.00 |
| CHEMBL341515 | — | — | 1 | - |
| CHEMBL126870 | — | — | 3 | - |
| CHEMBL339930 | — | — | 1 | - |
| CHEMBL424628 | — | — | 1 | - |
| CHEMBL127096 | — | — | 3 | - |
| CHEMBL340754 | — | — | 1 | - |
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | - |
| CHEMBL125918 | — | — | 1 | - |
| CHEMBL127637 | — | — | 3 | - |
| CHEMBL338403 | — | — | 1 | - |
| CHEMBL340512 | — | — | 1 | - |
| CHEMBL338804 | — | — | 1 | - |
| CHEMBL421443 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433859 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL127637 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL126870 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL433859 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL339930 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL424628 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL127096 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL433859 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL126870 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL340754 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL141 | LAMIVUDINE | IC50 | > | 100000.0 | nM | - |
| CHEMBL341515 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL338403 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL127096 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL340512 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL127637 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL338804 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL127637 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL421443 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL126870 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL127096 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL125918 | — | IC50 | > | 100000.0 | nM | - |