Assay Detail
Functional
CHEMBL680362
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The -logEC50 value of genistein on ACh-precontracted rings, where EC50 is the concentration causing 50% relaxation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
GENISTEIN AND FLUORINATED ANALOGS SUPPRESS AGONIST-INDUCED AIRWAY SMOOTH MUSCLE CONTRACTION
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.12 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL714 | ALBUTEROL | 4.0 | 1 | 7.12 |
| CHEMBL44 | GENISTEIN | 2.0 | 1 | - |
| CHEMBL1370561 | AMINOPHYLLINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL714 | ALBUTEROL | EC50 | = | 75.86 | nM | 7.12 |
| CHEMBL44 | GENISTEIN | EC50 | = | 194984.46 | nM | - |
| CHEMBL1370561 | AMINOPHYLLINE | EC50 | = | 524807.46 | nM | - |