Assay Detail
Binding
CHEMBL683429
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Compound was tested for inhibitory potency against Fatty-acid amide hydrolase (FAAH) at pH 9.0
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.29 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL414450 | — | — | 1 | 6.72 |
| CHEMBL422064 | — | — | 1 | 6.60 |
| CHEMBL157736 | — | — | 1 | 6.41 |
| CHEMBL155928 | — | — | 1 | 6.26 |
| CHEMBL347894 | — | — | 1 | 6.10 |
| CHEMBL157232 | — | — | 1 | 5.96 |
| CHEMBL345382 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL414450 | — | Ki | = | 190.0 | nM | 6.72 |
| CHEMBL422064 | — | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL157736 | — | Ki | = | 390.0 | nM | 6.41 |
| CHEMBL155928 | — | Ki | = | 550.0 | nM | 6.26 |
| CHEMBL347894 | — | Ki | = | 800.0 | nM | 6.10 |
| CHEMBL157232 | — | Ki | = | 1100.0 | nM | 5.96 |
| CHEMBL345382 | — | Ki | = | 1100.0 | nM | 5.96 |