Assay Detail
Functional
CHEMBL684533
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Compound was evaluated for its agonist potency by measurement of contraction of guinea pig aortic strips
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and adrenergic activity of ring-fluorinated phenylephrines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.65 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61372 | — | — | 1 | 4.96 |
| CHEMBL1215 | PHENYLEPHRINE | 4.0 | 1 | 4.57 |
| CHEMBL62072 | — | — | 1 | 4.41 |
| CHEMBL302451 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61372 | — | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL1215 | PHENYLEPHRINE | EC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL62072 | — | EC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL302451 | — | EC50 | = | 105000.0 | nM | - |